December 2, 2023

Microneedle Drug Delivery Market Share Soars Amidst Painless Revolution

The global healthcare landscape is on the brink of transformation as microneedle arrays (MNAs) take center stage, providing a painless and minimally invasive alternative to traditional hypodermic needle injections. With nearly 16 billion injections administered worldwide annually, the need for innovation in drug delivery methods has never been greater.

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Traditional hypodermic needles have long deterred patients due to pain perception, risks of needle-stick injuries, and the formidable barrier of the outermost skin layer, the stratum corneum. However, MNAs, designed to be virtually painless and technologically superior, are revolutionizing the field of transdermal drug delivery.

One of the key objectives of this groundbreaking technology is to create a larger transport pathway, allowing large molecules to pass through the skin, thus increasing permeability. This breakthrough offers numerous advantages, including self-administration, better patient compliance, faster onset of action, and improved efficacy. Additionally, it reduces the fear of needles, driving adoption in mass immunization programs and pediatrics.

Microneedle systems provide precise control over drug delivery rates, faster healing at injection sites, and the potential for dose reduction, enhancing overall drug efficacy. However, like any innovation, MNAs have their limitations, including the possibility of skin irritation in sensitive individuals and the risk of microneedle tip breakage.

The applications for microneedle drug delivery are diverse, encompassing therapies involving antibodies, antigens, proteins, and other biotechnological substances that are not adequately absorbed orally. Recent patent registrations reflect the growing interest in MNAs as a transdermal drug delivery system.

Cosmeceuticals and wearable epidermal diagnostic devices are also benefiting from the painless and noninvasive attributes of microneedle-based devices. The success of these minimally invasive devices promises a wide range of therapeutic opportunities for oral, buccal, ocular, and rectal drug delivery.

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Microneedles are typically classified into four categories: solid (coated and uncoated), dissolving, hydrogel, and hollow microneedles. Solid microneedles, made primarily of metal and silicon materials, have a long-standing presence in the market, with an emerging trend towards polymer-based solid microneedles.

Hollow and hydrogel microneedles are prominent segments, with hollow microneedles delivering higher quantities of active pharmaceutical ingredients (APIs). Dissolving microneedles, manufactured using biodegradable materials, are gaining attention for their eco-friendly API delivery.

Several companies are actively contributing to the global microneedle drug delivery market landscape through collaborations and research and development initiatives. NanoPass Technologies Ltd. has partnered with leading vaccine and immunotherapy companies to facilitate COVID-19 vaccine development, while Corium, Inc. is investigating MicroCor PTH (1-34) in collaboration with Eli Lilly’s Forteo® for osteoporosis treatment.

Prominent players in the market include 3M, Microdermics, Zosano Pharma Corporation, Nitto Denko Corporation, Becton, Dickinson and Company, Vaxxas Pty Ltd, Valeritas, Corium, Inc., TheraJect, Inc., LTS Lohmann Therapie-Systeme AG, Alza Corporation, and NanoPass Technologies Ltd.

The future of healthcare is looking brighter and less painful, thanks to microneedle drug delivery systems, which promise to improve the lives of patients worldwide.

Global Industry Analysis, Size, Share, Growth, Trends, and Forecast 2023-2030 – By Product, Technology, Grade, Application, End-user, Region: (North America, Europe, Asia Pacific, Latin America and Middle East and Africa)

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This press release first seen on Brilad