December 9, 2023

Lyophilization Equipment Market: A Comprehensive Growth Analysis

Lyophilization, a freeze-drying (dehydration) process, is gaining prominence as a crucial method for preserving perishable materials and enhancing the shelf-life and stability of medicinal products. This process has become indispensable in the pharmaceutical, biopharmaceutical, and biotechnology industries, and it is poised for significant growth in the coming years.

Extending Product Shelf-Life and Stability

Lyophilization enables the extension of product shelf-life, often up to 2-4 years, and facilitates the transportation of products stored at room temperature. It is extensively employed in the pharmaceutical industry to maintain the stability of complex drug formulations that are not stable in liquid form. Additionally, lyophilization enhances the stability of dry powders and products in a dry state, making it a vital tool for pharmaceutical manufacturers.

Growing Demand for Lyophilization Equipment

The consistently rising need for enhanced shelf-life for vaccines, injectables, and various drug products is fueling the global demand for lyophilization. This, in turn, is driving the sales of lyophilization equipment. Furthermore, the technology’s applications in large-scale manufacturing, food engineering and packaging, and pharmaceutical production are set to stimulate the growth potential of the global lyophilization equipment market.

Biopharma and Biotechnology Industries Drive Demand

The biopharma and biotechnology industries are experiencing significant growth, further boosting the demand for lyophilization equipment. Lyophilization is essential for preserving bulk pharmaceutical and biopharmaceutical ingredients, monoclonal antibodies, proteins, peptides, collagens, oligonucleotides, and enzymes. Industry statistics reveal that approximately 16% of the top 100 pharmaceutical drugs and around 35% of biologic drugs are lyophilized. With the robust growth of contract manufacturing organizations (CMOs) in the biopharma sector, the demand for lyophilization equipment is on the rise. The increasing demand for oligonucleotides and peptides, which require lyophilization for stability and extended shelf-life, is also contributing to this growth.

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Technological Advancements Drive Long-term Growth

Technological advancements in lyophilization equipment play a crucial role in the market’s long-term growth. Modern lyophilizers feature separated ice condensers and drying chambers to reduce cross-contamination, simultaneous defrosting and loading for standardized processes, and advanced controls and monitors for optimized operations. Automation with interlocks, safety alarms, vacuum pumps, and refrigeration systems further enhances the efficiency of lyophilization equipment. These innovations, coupled with increasing research and development in the pharmaceutical industry, will continue to drive demand for lyophilization equipment.

Lyophilized Vaccines in High Demand

The COVID-19 pandemic has highlighted the advantages of lyophilization, particularly for monoclonal antibody therapies, antibody-drug conjugates, and raw materials used in COVID-19 vaccines. Unlike existing vaccines that require ultra-cold storage, lyophilized vaccines only need standard refrigeration. This shift is evident with pharmaceutical giants like Pfizer and Russia exploring lyophilized vaccine formulations, signaling a growing trend in the industry.

Tray Freeze Dryers Dominate

In terms of technology, tray-style freeze dryers remain dominant in the global lyophilization equipment market. These freeze dryers are preferred for their wide range of applications in the pharmaceutical and food technology sectors and their ability to provide a higher degree of product lyophilization. With the increasing demand for frozen food, tray-style freeze dryers are expected to witness continued growth.

Meeting Surging Demand

Key players in the lyophilization equipment market are ramping up their production capacities to meet the surging demand. Companies such as Argonaut Manufacturing Services and LSNE Contract Manufacturing have expanded their facilities and capabilities to accommodate the growing need for lyophilization services.

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Global Industry Analysis (2018 – 2021) – Growth Trends and Market Forecast (2022 – 2029)

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This press release first seen on Brilad